hGDF15

Nomenclature

C57BL/6Smoc-Gdf15tm(hGDF15)Smoc

Cat. NO.

NM-HU-215002

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Faah

Model Description

The endogenous mice Gdf15 gene was replaced by human GDF15 gene.

Validation Data

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Fig1. Detection of GDF15 expression inintestiner and colon and liver  by RT-PCR. Wild type: only one band at 314 bp with primers F1/R1(mGdf15);Homozygous: only one band at 160 bp with primers F2/R2(hGDF15); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 2. Detection of hGDF15 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 3. Detection of mGDF15 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type.


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