hIL15-Tg(NMG)

Nomenclature

NOD.Cg-PrkdcscidIl2rgem1Tg(hIL15)Smoc

Cat. NO.

NM-KI-210141

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Il15

Synonyms

IL-15; AI503618

NCBI ID

16168

MGI ID

103014

Ensembl ID

ENSMUSG00000031712

Pubmed

Il15

Human Ortholog

IL15

Model Description

These transgenic mice harbor hIL15 expression cassettes.

Validation Data

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Fig1. Human IL15 expression analysis in hIL15-Tg(NMG) mice by ELISA.

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Fig2. Body weight of hIL15-Tg(NMG) post inoculation. 

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Fig3. Humanized immune reconstitution levels in hIL15-Tg(NMG) mice engrafted with human HSC.

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Fig4. hIL15-Tg(NMG) mice engrafted with human HSCs exhibit high expression of functional proteins such as NKG2D, Granzyme B, and NKp46.

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