hSIGLEC8(2)
Nomenclature
C57BL/6JSmo-Siglecftm1(hSIGLEC8)Smoc
Cat. NO.
NM-HU-210033
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Siglecf
Model Description
Validation Data
Fig1. Strain specific SIGLEC8 expression analysis in homozygouse hSIGLEC8 mice by flow cytometry. Spleen derived eosinophils were collected and analyzed by flow cytometry with species-specific anti-hSIGLEC8 and anti-mSIGLEC-F antibody. hSIGLEC8 was detectable in hSIGLEC8 mice but not in WT mice, mSIGLEC-F was detectable in WT mice but not in hSIGLEC8 mice.
Fig2. Strain specific SIGLEC8 expression analysis in homozygouse hSIGLEC8 mice by flow cytometry. Eosinophils of PBMC were collected from WT and homozygouse hSIGLEC8 mice, and analyzed by flow cytometry with species-specific anti-hSIGLEC8 and anti-mSIGLEC-F antibody. hSIGLEC8 was detectable in a small proportion of eosinophils in hSIGLEC8 mice, and the mSIGLEC-F was not expressed.
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