hCCL4

Nomenclature

C57BL/6Smoc-Ccl4tm1(hCCL4)/Smoc

Cat. NO.

NM-HU-210013

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ccl4

Synonyms

Act-2; Mip1b; Scya4; MIP-1B; AT744.1

NCBI ID

20303

MGI ID

98261

Ensembl ID

ENSMUSG00000018930

Pubmed

Ccl4

Human Ortholog

CCL4

Model Description

The endogenous mice Ccl4 gene was replaced by human CCL4 gene
Research Application：drug screening

Validation Data

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Fig1. Detection of CCL4 expression in small intestine, spleen and  thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.

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