hPVRIG

Nomenclature

C57BL/6Smoc-Pvrigtm1(hPVRIG)/Smoc

Cat. NO.

NM-HU-210008

Strain State

Repository Live

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Gene Summary

Gene Symbol
Pvrig

Synonyms

Gm36869

NCBI ID

102640920

MGI ID

5596028

Ensembl ID

ENSMUSG00000109713

Pubmed

Pvrig

Human Ortholog

PVRIG

Model Description

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.
Research Application：drug screening

Validation Data

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Fig1. Detection of PVRIG expression in spleen by RT-PCR. 

Wild type: only one band at 291 bp with primers F1/R1(mPvrig); Homozygous: only one band at 351 bp with primers F2/R2(hPVRIG); Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hPVRIG expression in Daudi cells.

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Fig3. Detection of hPVRIG expression in Spleen in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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Fig4. Detection of hPVRIG expression in Blood in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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