hVSIG4
Nomenclature
C57BL/6Smoc-Vsig4tm1(hVSIG4)/Smoc
Cat. NO.
NM-HU-210004
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Vsig4
Model Description
Validation Data
Fig1. Analysis of human VSIG4 expression on the peritoneal exudate macrophages by FACS.
The homozygous KI mouse expresses human VSIG4 on the peritoneal exudate macrophages.
Fig.2 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.
Body weight were measured twice a week of hVSIG4 mice (n=4 , 3 male and 1 female). (A) Body weight. (B) Body weight change.
Fig.3 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.
Tumor volume were measured twice a week of hVSIG4 mice. MC38 (1×106) were inoculated subcutaneously into hVSIG4 mice (6-8-week-old, n=4, 3 male and 1 female). (A) Tumor volume. (B) Relative tumor volume.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreSMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn more
