hHLA-A11.1

Nomenclature

C57BL/6Smoc-H2-K1tm1(hHLA-A*1101)Smoc

Cat. NO.

NM-HU-204987

Strain State

Repository Live

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Gene Summary

Gene Symbol
H2-K1

Synonyms

K-f; H-2K; H2-K; H2-D1; H2-K_p; H-2K(d)

NCBI ID

14972

MGI ID

95904

Ensembl ID

ENSMUSG00000061232

Pubmed

H2-K1

Human Ortholog

HLA-A;HLA-E;HLA-F

Model Description

The endogenous mice H2-K1 gene was replaced by human HLA-A11.1 gene.

Validation Data

image.png

Fig1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.

Wild type: only one band at 369 bp with primers F1/R1(mH2-k1);

Heterozygous: one band at 369 bp with primers F1/R1(mH2-k1) and one band at 215 bp with primers F2/R2(hHLA-A11).

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of HLA-A11 expression in blood in HLA-A11 KI mice.

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