hSOST

Nomenclature

C57BL/6Smoc-Sosttm1(hSOST)Smoc

Cat. NO.

NM-HU-200251

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Sost

Synonyms

5430411E23Rik

NCBI ID

74499

MGI ID

1921749

Ensembl ID

ENSMUSG00000001494

Pubmed

Sost

Human Ortholog

SOST

Model Description

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Validation Data

image.png

Fig.1 Detection of SOST expression in heart by RT-PCR. 

Wild type: only one band at 195 bp with primers F1/R1 (mSost);

Homozygous: only one band at 138 bp with primers F2/R2 (hSOST); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hSOST expression in plasma by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

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