hPDGFRA

Nomenclature

C57BL/6Smoc-Pdgfratm1(hPDGFRA)Smoc

Cat. NO.

NM-HU-200250

Strain State

Repository Live

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Gene Summary

Gene Symbol
Pdgfra

Synonyms

CD140a; Pdgfr-2; AI115593

NCBI ID

18595

MGI ID

97530

Ensembl ID

ENSMUSG00000029231

Pubmed

Pdgfra

Human Ortholog

PDGFRA

Model Description

The endogenous mice Pdgfra gene was replaced by human PDGFRA gene.

Validation Data

image.png

Fig.1 Detection of PDGFRA expression in cortex of WT C57BL/6 and HO hPDGFRA mice by RT-PCR (9-week-old, female). 

Wild type: only one band at 787 bp with primers F1/R1(mPdgfra);

Homozygous: only one band at 821 bp with primers F2/R2(hPDGFRA).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human PDGFRA expression in hPDGFRA knockin mice by WB (9-week-old, female). 

Abbr. M, marker; WT, wild type; HO, Homozygous.

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