hIL21

Nomenclature

C57BL/6Smoc-Il21tm1(hIL21)Smoc

Cat. NO.

NM-HU-200255

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
IL21

Synonyms

IL-21

NCBI ID

60505

MGI ID

1890474

Ensembl ID

ENSMUSG00000027718

Pubmed

IL21

Human Ortholog

IL21

Model Description

The endogenous mice Il21 gene was replaced by human IL21 gene.

Validation Data

image.png

Fig1. Detection of IL21 expression in splenocyte  by RT-PCR. 

Wild type: only one band at 272 bp with primers F1/R1(mIl21);

Homozygous: only one band at 304 bp with primers F2/R2(hIL21); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hIL21 expression in splenocyte culture supernatants by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

Note. hIL21 and C57BL/6 mice were stimulated with ConA in vitro.

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