hDLL3

Nomenclature

C57BL/6Smoc-Dll3tm1(hDLL3)Smoc

Cat. NO.

NM-HU-200231

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Dll3

Synonyms

pu; pudgy

NCBI ID

13389

MGI ID

1096877

Ensembl ID

ENSMUSG00000003436

Pubmed

Dll3

Human Ortholog

DLL3

Model Description

The endogenous mice Dll3 gene was replaced by human DLL3 gene.

Validation Data

image.png

Fig.1 Detection of DLL3 expression in brain by RT-PCR. 

Wild type: only one band at 293 bp with primers F1/R1 (mDll3);

Homozygous: only one band at 282 bp with primers F2/R2 (hDLL3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human DLL3 expression in hDLL3 knockin mice by WB. 

Abbr. HO, homozygous; WT, wild type.

Note: The anti-human DLL3 antibody cross-reacted with mouse DLL3 and humanized DLL3.


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