hCTLA-4/hCD28(BALB/c)

Nomenclature

BALB/cAnSmoc-Ctla4tm1(hCTLA4)Cd28tm1(hCD28)Smoc

Cat. NO.

NM-HU-200226

Strain State

Sperm cryopreservation

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Model Description

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.
Research Application：Immunotherapy

Validation Data

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Fig1. Analysis of human CTLA4(hCD152) expression in the spleen by FACS . The homozygous KI mouse expresses human CTLA4 on T cells.

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Fig2. Analysis of human CD28 expression in the spleen by FACS . The homozygous KI mouse expresses human CD28 on T cells.

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