hANGPT2

Nomenclature

C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc

Cat. NO.

NM-HU-200247

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Angpt2

Synonyms

Ang2; Agpt2; Ang-2

NCBI ID

11601

MGI ID

1202890

Ensembl ID

ENSMUSG00000031465

Pubmed

Angpt2

Human Ortholog

ANGPT2

Model Description

The endogenous mice Angpt2 gene was replaced by human ANGPT2 gene.

Validation Data

image.png

Fig.1 Detection of ANGPT2 expression in kidney by RT-PCR. 

Wild type: only one band at 188 bp with primers F1/R1(mAngpt2);

Homozygous:  only one band at 523 bp with primers F2/R2(hANGPT2). 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human ANGPT2 expression in serum by ELISA. (n=3 male in both groups)

Abbr.  HO, homozygous; WT, wild type.

Note. The human ANGPT2 ELISA kit cross-reacted with mANGPT2 and humanized ANGPT2.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more