hFCRN(NMG)

Fig.1 Detection of FCRN expression in kidney by RT-PCR. 

Wild type: only one band at 181 bp with primers F1/R1(mFcgrt);

Heterozygous: one band at 181 bp with primers F1/R1(mFcgrt) and one band at 310 bp with primers F2/R2(hFCGRT). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

Fig.2 Detection of human FCRN expression in hFCRN (NMG) mice by WB. 

Abbr. M, marker; WT1, wild type, NOD-Scid; WT2, wild type, NMG; HE, heterozygous; PC, positive control, hFCRN (NM-HU-190070).

Fig.3 PK study of Trastuzumab deruxtecan in hFCRN (NMG) mice. (In cooperation with the third party)

Abbr. Hom, homozygous; WT, wild type.