hC1R

Nomenclature

C57BL/6Smoc-C1raem1(hC1R)/Smoc

Cat. NO.

NM-HU-2000075

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
C1ra

Synonyms

C1r; mC1rA; AI132558

NCBI ID

50909

MGI ID

1355313

Ensembl ID

ENSMUSG00000055172

Pubmed

C1ra

Human Ortholog

C1RA

Model Description

The endogenous mouse C1ra gene was replaced by human C1R gene.
Research Application：Immunotherapy,drug screening

Validation Data

image.png

Fig1. Detection of C1R expression in bladder and liver by RT-PCR. 

Wild type: only one band at 443 bp with primers F1/R1(mC1r);

Homozygous: only one band at 174 bp with primers F2/R2(hC1R); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hC1R expression in serum by ELISA (n=6). 

Abbr. HO, homozygous; WT, wild type.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more