hCCL1

Nomenclature

C57BL/6Smoc-Ccl1tm2(hCCL1)/Smoc

Cat. NO.

NM-HU-2000074

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ccl1

Synonyms

I-309; Scya1; Tca-3; BF534335

Chromosome

11

NCBI ID

20290

MGI ID

98258

Ensembl ID

ENSMUSG00000020702

Pubmed

Ccl1

Human Ortholog

CCL1

Model Description

The endogenous mouse Ccl1 gene was replaced by human CCL1 gene.
Research Application：Immunotherapy,drug screening

Validation Data

image.png

Fig.1 Detection of CCL1 expression in thymus by RT-PCR. 

Wild type: only one band at 197 bp with primers F1/R1(mCcl1);

Homozygous: only one band at 194 bp with primers F2/R2(hCCL1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCCL1 and mCCL1 expression in serum by ELISA (6-8wks, female, n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. hCCL1 and C57BL/6 mice were i.p. injected with con.A for 3h.

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