hFCGR2A

Nomenclature

C57BL/6Smoc-Fcgr2btm3(hFCGR2A)/Smoc

Cat. NO.

NM-HU-2000071

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Fcgr2b

Synonyms

AI528646; CD32; F630109E10Rik; Fc[g]RII; FcgRII; Fcgr2; Fcgr2a; Fcr-2; Fcr-3; Ly-17; Ly-m20; LyM-1; Lym-1; fcRII

Chromosome

1

NCBI ID

14130

MGI ID

95499

Ensembl ID

ENSMUSG00000026656

Pubmed

Fcgr2b

Model Description

The endogenous mouse Fcgr2b gene was replaced by human FCGR2A gene.
Research Application：Immunotherapy,drug screening

Validation Data

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Fig 1. Detection of hCD32a and mCD32 expression in Peripheral blood in WT C57BL/6 and HO hFCGR2A KI mice (male, 5-10wks). 

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Fig 2. Detection of hCD32a and mCD32 expression in Spleen in WT C57BL/6 and HO hFCGR2A KI mice (male, 5-10wks).

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Fig 3. Detection of hCD32a and mCD32 expression in Bone marrowin WT C57BL/6 and HO hFCGR2A KI mice (male, 5-10wks). 

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