hNR1I2

Nomenclature

C57BL/6Smoc-Nr1i2tm3(hNR1I2)/Smoc

Cat. NO.

NM-HU-2000066

Strain State

Repository Live

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Gene Summary

Gene Symbol
Nr1i2

Synonyms

PXR; SXR; PXR1; mPXR; PXR.1; PXR.2

NCBI ID

18171

MGI ID

1337040

Ensembl ID

ENSMUSG00000022809

Pubmed

Nr1i2

Human Ortholog

NR1I2

Model Description

The endogenous mouse Nr1i2 gene was replaced by human NR1I2 gene.
Research Application：Pharmacokinetic-related model

Validation Data

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Fig1. Detection of NR1I2 expression by RT-PCR. 

Wild type: only one band at 228 bp with primers F2/R2(mNr1i2);

Homozygous: only one band at 172 bp with primers F1/R1(hNR1I2); 

Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.


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