hTSLP

Nomenclature

C57BL/6Smoc-Tslptm2(hTSLP)/Smoc

Cat. NO.

NM-HU-2000064

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
TSLP

Synonyms

NCBI ID

53603

MGI ID

1855696

Ensembl ID

ENSMUSG00000024379

Pubmed

TSLP

Human Ortholog

TSLP

Model Description

The endogenous mouse Tslp gene was replaced by human TSLP gene.
Research Application：Asthma research；drug screening

Validation Data

image.png

Fig.1 Detection of TSLP expression in bladder by RT-PCR. 

Wild type: only one band at 168 bp with primers F1/R1 (mTslp);

Homozygous: only one band at 160 bp with primers F2/R2 (hTSLP); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTSLP and mTSLP expression in thymus homogenate by ELISA (n=5). 

Abbr. HO, homozygous; WT, wild type.

Note. hTSLP and C57BL/6 mice were i.p. injected with LPS.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more