hDLL4

Nomenclature

C57BL/6Smoc-Dll4tm1(hDLL4)Smoc

Cat. NO.

NM-HU-2000020

Strain State

Repository Live

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Gene Summary

Gene Symbol
Dll4

Synonyms

Delta4

NCBI ID

54485

MGI ID

1859388

Ensembl ID

ENSMUSG00000027314

Pubmed

Dll4

Human Ortholog

DLL4

Model Description

The endogenous mouse Dll4 gene was replaced by human DLL4 gene.
Research Application：Immunotherapy,drug screening

Validation Data

image.png

Fig.1 Detection of DLL4 expression in lung by RT-PCR. 

Wild type: only one band at 450 bp with primers F1/R1(mDll4);

Homozygous:  only one band at 468 bp with primers F2/R2(hDLL4).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig. 2 Detection of human DLL4 expression in the lung of hDLL4 mice by WB. (male in both groups)

Abbr. M, marker; WT, wild type; HO, Homozygous.

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