hSIGLEC15
Nomenclature
C57BL/6JSmo-Siglec15tm1(hSIGLEC15)Smoc
Cat. NO.
NM-HU-190037
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
SIGLEC15
Model Description
Validation Data
Fig1. In vivo validation of humanized SIGLEC15 mice. Humanized SIGLEC15 mice were inoculated with MC38 colon cancer cells, and were randomly assigned into different groups when the tumors grew to a volume of 100 mm3. Human-specifc, SIGLEC15 antibody ( 5G12-hIgG1 ) was given twice a week (BIW) for two weeks (In collaboration with Crownbio).
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