hSTING
Nomenclature
C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Cat. NO.
NM-HU-190036
Strain State
Embryo cryopreservation
Model Description
Validation Data
Fig1 The expression of human STING in CD4+ T lymphocytes of humanized STING mice was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in CD4+ T lymphocytes derived from blood, spleen, thymus and lymph node.
Fig2 The expression of human STING in CD8+ T lymphocytes of humanized STING mice was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in CD8+ T lymphocytes derived from blood, spleen, thymus and lymph node.
Fig3 The expression of human STING in the heart and lung cells was measured by FACS. In heterozygous humanized STING mice, active expression of human STING was detected in the heart and lung cells .
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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