hCD28

Nomenclature

C57BL/6Smoc-Cd28tm2(hCD28)Smoc

Cat. NO.

NM-HU-190011

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CD28

Synonyms

NCBI ID

12487

MGI ID

88327

Ensembl ID

ENSMUSG00000026012

Pubmed

CD28

Human Ortholog

CD28

Model Description

The endogenous mouse Cd28 gene was replaced by human CD28 gene.
Research Application：Immune-related

Validation Data

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Fig1. Expression characterization of hCD28 on T cells in blood in heterozygous hCD28 KI mice.

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Fig2. Expression characterization of hCD28 on CD4+ and CD8+ T cells in blood in heterozygous hCD28 KI mice.

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Fig3. Expression characterization of hCD28 on CD4+ and CD8+ T cells in blood in homozygous hCD28 KI mice.

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Fig4. Cytokine release post stimulation with anti-CD28 antibodies in vitro.

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