hTLR9

Nomenclature

C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc

Cat. NO.

NM-HU-18016

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
TLR9

Model Description

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Research Application:drug screening

Validation Data

image.png

Fig.1 Detection of hTLR9 and mTlr9 expression in Peripheral blood in WT C57BL/6 and HO hTLR9 KI mice. 

image.pngFig.2 Detection of hTLR9 and mTlr9 expression in Spleen in WT C57BL/6 and HO hTLR9 KI mice.


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