hPD-L1/hLAG3

Nomenclature

C57BL/6Smoc-Cd274tm1(hPD-L1)Lag3tm1(hLAG3)Smoc

Cat. NO.

NM-HU-00137

Strain State

Embryo cryopreservation

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Model Description

hPD-L1（NM-HU-00062）was crossed with hLAG3（NM-HU-00049）to generate hPD-L1/hLAG3.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

pd-l1&lag3.png


Fig1 Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. mPDL1+ and mLAG3+ were detectable in wild type (WT) C57BL/6, while hPDL1+ and hLAG3+ cells were detectable in the homozygous hPDL1/hLAG3 mice.

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