hIL17A

Nomenclature

C57BL/6Smoc-Il17atm1(hIL17A)Smoc

Cat. NO.

NM-HU-00042

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
IL17A

Synonyms

Il17; Ctla8; IL-17; Ctla-8; IL-17A

NCBI ID

16171

MGI ID

107364

Ensembl ID

ENSMUSG00000025929

Pubmed

IL17A

Human Ortholog

IL17A

Model Description

The endogenous mouse Il17a gene was replaced by human IL17A gene.
Research Application：Immunotherapy,cancer research,drug screening

Validation Data

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Fig1. Detection of IL-17A expression in Large Intestine by RT-PCR. Wild type: only one band at 100 bp with primers F1/R1(mIl-17a);Homozygous: only one band at 121 bp with primers F2/R2(hIL-17A); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL17A.png

Fig2. Expression of human IL17A in cell supernatant derived from splenocytes  of IL17A-HU homozygous mice is detected by Elisa.

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