hCD4
Nomenclature
C57BL/6Smoc-Cd4tm1(hCD4) Smoc
Cat. NO.
NM-HU-00115
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Cd4
Model Description
Validation Data


Fig 1. Flow cytometric analysis of the T cell subtype proportions in peripheral blood from control and the humanized CD4 mouse model.
A Lymphocyte dot plots. The gate for lymphocytes is indicated. B Statistical analyses of the CD8+ T cell and CD4+ T cell in the indicated groups. *P<0.05,**P<0.01.


Fig2. Flow cytometric analysis of the T cell subtype proportions in thymus from control and the humanized CD4 mouse model. A Lymphocyte dot plots. The gate for lymphocytes is indicated. B Statistical analyses of the CD8+ T cell and CD4+ T cell in the indicated groups. *P<0.05.

Fig3. Expression characterization of hCD4 in hCD4 KI mice.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreSMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn more