hGCGR(SD)

Nomenclature

SD-Gcgrem2(hGCGR)Smoc

Cat. NO.

NR-HU-225066

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gcgr

Model Description

The endogenous rat Gcgr gene was replaced by human GCGR gene.

Validation Data

image.png

Fig.1 Detection of GCGR expression in the cerebellum by RT-PCR. 

Wild type: only one band at 178 bp with primers F1/R1(rGcgr);

Homozygous: only one band at 180 bp with primers F2/R2(hGCGR).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GCGR expression in hGCGR knockin rat by WB. (male, 14wks)

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human GCGR antibody cross-reacted with rat GCGR and humanized GCGR.


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