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Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

mouse	hSERPINA1 Strain Name：C57BL/6JSmo-Serpina1e^{tm1(hSERPINA1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-225055
mouse	hSORT1 Strain Name：C57BL/6JSmo-Sort1^{tm1(hSORT1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-225035
mouse	hTFR1 Strain Name：C57BL/6JSmo-Tfrc^{tm1(hTFRC)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-215059
mouse	hTM4SF1 Strain Name：C57BL/6JSmo-Tm4sf1^{tm(hTM4SF1)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-230066
mouse	hTP53(2) Strain Name：C57BL/6JSmo-Trp53^{tm2(hTP53)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-225052
mouse	hTPBG Strain Name：C57BL/6JSmo-Tpbg^{tm1(hTPBG)Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-200239
mouse	hTREM2(2) Strain Name：C57BL/6JSmo-Trem2^{tm(hTREM2)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-220502
mouse	hTROP2 Strain Name：C57BL/6JSmo-Tacstd2^{tm(hTACSTD2)Smoc} Strain State：Repository Live \| Cat. NO.：NM-HU-215022
mouse	hVEGFR2 Strain Name：C57BL/6JSmo-Kdr^{tm2(hKDR) Smoc} Strain State：Embryo cryopreservation \| Cat. NO.：NM-HU-00098 Research Application：Immunotherapy,cancer research,drug screening
mouse	pAtp4b-hCLDN18.2-Tg Strain Name：C57BL/6JSmo-Tg(pAtp4b-hCLDN18.2)1Smoc Strain State：Sperm cryopreservation \| Cat. NO.：NM-TG-220197

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