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Models

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

mouse
hPD-L2
Strain Name：C57BL/6JSmo-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190050
Research Application：Immunotherapy,cancer research,drug screening
mouse
hPD-L2(BALB/c)
Strain Name：BALB/cJSmo-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190061
Research Application：Immunotherapy,cancer research,drug screening
mouse
hPLK1
Strain Name：C57BL/6JSmo-Plk1tm1(hPLK1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225083
mouse
hPSCA
Strain Name：C57BL/6JSmo-Pscatm(hPSCA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-230059
mouse
hPSMA
Strain Name：C57BL/6JSmo-Folh1tm1(hPSMA-Wpre-PA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200240
mouse
hPTPN1
Strain Name：C57BL/6JSmo-Ptpn1tm1(hPTPN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225059
mouse
hPVR
Strain Name：C57BL/6JSmo-Pvrtm1(hPVR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190012
Research Application：Immune-related
mouse
hPVRL2
Strain Name：C57BL/6JSmo-Nectin2tm1(hNECTIN2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000084
Research Application：Immunotherapy,drug screening
mouse
hSDC1
Strain Name：C57BL/6JSmo-Sdc1tm1(hSDC1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000026
Research Application：Immunotherapy,drug screening
mouse
hSEMA4D
Strain Name：C57BL/6JSmo-Sema4dtm1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117
Research Application：Immunotherapy,cancer research,drug screening
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