Fos-CreERT2

Nomenclature

C57BL/6Smoc-Fosem1(CreERT2-SV40-pA)Smoc

Cat. NO.

NM-KI-200110

Strain State

Repository Live

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Gene Summary

Gene Symbol
Fos

Synonyms

cFos; c-fos; D12Rfj1

NCBI ID

14281

MGI ID

95574

Ensembl ID

ENSMUSG00000021250

Pubmed

Fos

Human Ortholog

FOS

Model Description

A CreERT2 expression cassette was knocked into the Fos gene start codon site.
Research Application：Cre recombinase tool

Validation Data

image.png

Fig. 1 Detection of tdTomato (red) in different regions of brain derived from FosCreERT2/+; Rosa26tdTomato/+ mouse. 

CreERT2-mediated recombination in the brian can be induced by tamoxifen after formalin injection into the mouse hind paw. 

Publications

Reversal of hyperactive higher-order thalamus attenuates defensiveness in a mouse model of PTSD
References：SCIENCE ADVANCES

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