Klk6-KO(2)
Nomenclature
C57BL/6JSmo-Klk6em3Smoc
Cat. NO.
NM-KO-250710
Strain State
Repository Live
Gene Summary
Gene Symbol
Klk6
Model Description
鉴定报告
DownloadValidation Data

Fig.1 Detection of Klk6 expression in cerebellum by RT-PCR. Tissue RNA was extracted from wild-type C57BL/6 mice (WT) and homozygous Klk6-KO(2) mice (HO) (n=2, male, 8-10 weeks old), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers.
Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig.2 Detection of Klk6 expression in cerebellum by qPCR. Tissue RNA was extracted from wild-type C57BL/6 litters (WT) and homozygous Klk6-KO(2) mice (HO) (n=2, male, 8-10 weeks old), then cDNA libraries were synthesized by reverse transcription, followed by qPCR with mouse Klk6 and mouse Gapdh primers. Relative expression represents mouse Klk6 mRNA levels relative to its average expression in WT mice.
You may also like
Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
Learn moreCre-lox系统介绍及使用汇总
你一定听说过Cre-lox重组系统,无论你是否直接进行过基因操作。由于Cre-lox系统具有操作简单、重组率高的优点,如今已经成为体内外遗传操作的强有力工具。利用Cre-lox系统,可以在特定细胞、组织或整个生物体,甚至在特定时间点敲除或表达某个基因,实现对特定基因的时空特异性操作,这对基因功能的研究和人类疾病动物模型的建立都具有深刻影响。
Learn more