hLDLR

Nomenclature

C57BL/6Smoc-Ldlrtm1(hLDLR)Smoc

Cat. NO.

NM-HU-230148

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Ldlr

Model Description

The endogenous mouse Ldlr gene was replaced by human LDLR gene.

Validation Data

image.png

Fig.1 Detection of LDLR expression in colon and liver by RT-PCR. 

Wild type: only one band at 182 bp with primers F1/R1(mLdlr);

Heterozygous: one band at 182 bp with primers F1/R1(mLdlr) and one band at 198 bp with primers F2/R2(hLDLR). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more