hGIPR
Nomenclature
C57BL/6Smoc-Giprtm1(hGIPR)Smoc
Cat. NO.
NM-HU-225064
Strain State
Repository Live
Gene Summary
Gene Symbol
Gipr
Model Description
Validation Data
Fig.1 Detection of GIPR expression in brain by RT-PCR.
Wild type: only one band at 177 bp with primers F1/R1 (mGipr);
Homozygous: only one band at 343 bp with primers F2/R2 (hGIPR).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig. 2 Detection of human GIPR expression in hGIPR mice by WB.
Abbr. M,marker; HO, homozygous; WT, wild type; BAT, brown adipose tissue.
Note. The anti-human GIPR Antibody cross-reacted with mouse GIPR and humanized GIPR.
Fig. 3 In vivo function of hGIP in IPGTT. Concentration of Plasma glucose were measured after intraperitoneal injection of glucose and 50 nM/kg human GIP (Cat. HY-P0276, MCE) in 6-8 weeks old wild-type C57BL/6 male mice and hGIPR male mice (n = 6); Average ± SEM; *p<0.05, **p<0.01, ***p<0.001; (Student’s t test).
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