Tubb3-2A-CreERT2-2A-tdTomato
Nomenclature
C57BL/6Smoc-Tubb3em1(P2A-CreERT2-T2A-tdTomato-WPRE-pA)Smoc
Cat. NO.
NM-KI-240472
Strain State
Sperm cryopreservation
Gene Summary
Gene Symbol
Tubb3
Model Description
鉴定报告
DownloadValidation Data
Fig1. CreERT2 mediated recombination in cerebellum of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Fig2. CreERT2 mediated recombination in DRG of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Fig3. Detection of zsGreen(Green) and tdTomato(red) in various tissues of Tubb3CreERT2/+; Rosa26zsGreen/+ mouse.
Following tamoxifen induction, tissues expressing zsGreen included the brain, spinal cord, reproductive system, skin, pituitary gland and dorsal root ganglia. Tissues with low levels of zsGreen expression included the heart, lung, and liver.
In the absence of tamoxifen induction, low-level leaky expression of zsGreen was observed in the brain, spinal cord, dorsal root ganglia, and pituitary gland.
Regarding tdTomato, minor expression was observed in the brain, while no obvious expression was detected in other tissues.
(31-days old, male) (For more detailed information please contact our technical advisor.)
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreSMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn more
