Cyp19a1-IRES-Cre

Nomenclature

C57BL/6Smoc-Cyp19a1em(IRES-Cre)Smoc

Cat. NO.

NM-KI-215089

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cyp19a1

Synonyms

Ar; ArKO; Int5; Cyp19; Int-5; p450arom

NCBI ID

13075

MGI ID

88587

Ensembl ID

ENSMUSG00000032274

Pubmed

Cyp19a1

Human Ortholog

CYP19A1

Model Description

IRES-Cre expression cassette was knocked into the Cyp19a1 gene .

Validation Data

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Fig 1. Cre-mediated recombination in ovary of Cyp19a1Cre/+; Rosa26tdTomato/+ mice.

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Fig 2. Cre-mediated recombination in testis of Cyp19a1Cre/+; Rosa26tdTomato/+ mice.

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Fig 3. Cre-mediated recombination in brain of Cyp19a1Cre/+; Rosa26tdTomato/+ female mice.

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Fig 4. Cre-mediated recombination in brain of Cyp19a1Cre/+; Rosa26tdTomato/+ male mice.

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Fig 5. Detection of tdTomato (red) in various tissues of Cyp19a1Cre/+; Rosa26tdTomato/+ female mice. 

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Fig 6. Detection of tdTomato (red) in various tissues of Cyp19a1Cre/+; Rosa26tdTomato/+ male mice. Expression tissues include: brain, cornea, heart, lungs, liver, stomach, salivary glands, adrenal glands, kidneys, pancreas, small intestine, colon, spleen, testis, thymus. A few cells expressed in brown fat, spinal cord, muscle, skin. (12-week old, male) (For more detailed information please contact our technical advisor.) 

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