Shh-EGFP-Cre

Nomenclature

C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc

Cat. NO.

NM-KI-200232

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Shh

Synonyms

Hx; Dsh; Hhg1; Hxl3; ShhNC; M100081; 9530036O11Rik

Chromosome

5

NCBI ID

20423

MGI ID

98297

Ensembl ID

ENSMUSG00000002633

Pubmed

Shh

Human Ortholog

SHH

Model Description

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.
Research Application：Cre tool mice

Validation Data

image.png

Fig1. Cre mediated recombination in hindpaw and forepaw of ShhEGFP-Cre/+; Rosa26tdTomato/+ mouse. 

Shh-2A-Cre 4#.jpg


Fig3. Detection of tdTomato(red) and EGFP(Green) in various tissues of ShhEGFP-Cre/+; Rosa26tdTomato/+ mouse. Expression of tdTomato was observed in the following tissues: brain, spleen, liver, lungs, kidneys, hind paws, reproductive system, adrenal glands, large intestine, small intestine, skin, and forepaws.

EGFP expression was detected in: liver, reproductive system, large intestine, and small intestine.

(45-days old, male) (For more detailed information please contact our technical advisor.) 


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more