Csf1r-IRES-Cre

Nomenclature

C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc

Cat. NO.

NM-KI-190026

Strain State

Repository Live

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Gene Summary

Gene Symbol
CSF1R

Model Description

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.
Research Application:Cre recombinase tool

Validation Data

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Fig1. Flow assay of fluorescent gene expression in peripheral blood macrophages of Csf1r-Cre+/-;R26-mTmG+/- mice. In cre-expressing F4/80 macrophages, tdTomato was excised and the cells were labelled with EGFP; in F4/80 macrophages without cre expression, the cells were labelled with tdtomato and EGFP was not expressed.

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Fig2. Cre mediated recombination in skin of Csf1r Cre/+;Rosa26 tdTomato/+ mice.

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Fig3. Detection of tdTomato(red) in various tissues of Csf1r Cre/+;Rosa26 tdTomato/+ mice. The tissues that express tdTomato include: brain, eyeball, heart, lungs, liver, salivary glands, kidneys, small intestine, large intestine, ovaries, skin, adrenal gland, gallbladder. A small amount of expressiontdTomato are spinal cord. (7.5-weeks old, female) (For more detailed information please contact our technical advisor.) 


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