Abcc2-KO(SD)
Nomenclature
SD-Abcc2em1Smoc
Cat. NO.
NR-KO-200002
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Abcc2
Model Description
Exon 4-6 of Abcc2 gene was deleted to generate Abcc2 knockout rat.
Research Application：Dubin-Johnson Syndrome research. Drug metabolism research.
*Literature published using this strain should indicate: Abcc2-KO(SD) rats (Cat. NO. NR-KO-200002) were purchased from Shanghai Model Organisms Center, Inc..
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Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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