Abcb1b-KO(SD)
Nomenclature
SD-Abcb1bem1Smoc
Cat. NO.
NR-KO-250185
Strain State
Developing
Gene Summary
Gene Symbol
Abcb1b
Model Description
The exon 4 of Abcb1b gene was deleted to generate Abcb1b knockout rat.
*Literature published using this strain should indicate: Abcb1b-KO(SD) rats (Cat. NO. NR-KO-250185) were purchased from Shanghai Model Organisms Center, Inc..
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Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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