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Models

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

mouse
pCdh16-hENPP3-Tg
Strain Name：C57BL/6JSmo-Tg(pCdh16-hENPP3)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220195
mouse
pWap-hHER2-TG
Strain Name：C57BL/6JSmo-Tgtn(pWap-ERBB2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225013
mouse
R26-CAG-hFcRn
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-hFcRn)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00081
Research Application：cancer research；Immunotherapy,drug screening
mouse
R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190068
Research Application：cancer research
mouse
R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190067
Research Application：cancer research
mouse
R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR (T790M) -IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190070
Research Application：cancer research
mouse
R26-CAG-LSL-hEGFR-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EGFR-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190066
Research Application：cancer research
mouse
R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010
Research Application：cancer
mouse
R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-emL4-ALK-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190072
Research Application：cancer research
mouse
R26-CAG-LSL-hEZH2*Y646N-IRES-Luc-2A-tdTomato
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-EZH2(Y646N)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190073
Research Application：cancer research
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