Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Abcb11em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18010
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Strain Name：C57BL/6Smoc-Abcb1aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200904
Disease Connection：Niemann-Pick disease, inflammatory bowel disease 13
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Strain Name：FVB-Abcb1aem1Abcb1bem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191211
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Strain Name：C57BL/6Smoc-Abcb1bem/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220491
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Strain Name：C57BL/6Smoc-Abcb1bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-233861
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Strain Name：FVB-Abcb4em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200584
Disease Connection：cholecystitis, cholestasis, hepatocellular carcinoma, intrahepatic cholestasis, primary sclerosing cholangitis
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