Alb-CreERT2

Nomenclature

B6.129S-Albtm1.1(CreERT2)Smoc

Cat. NO.

NM-KI-00002

Strain State

Repository Live

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Gene Summary

Gene Symbol
ALB

Synonyms

Alb1; Alb-1; BCL002

NCBI ID

11657

MGI ID

87991

Ensembl ID

ENSMUSG00000029368

Pubmed

ALB

Human Ortholog

ALB

Model Description

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.
Research Application：cre-mediated recombination system

Validation Data

alb-creERT2-1.png

Fig1 X-gal staining of liver slides of Alb-CreERT2 and LacZ positive mouse before and after tamoxifen injection. 

alb-creERT2-2.png

Fig2  Immunofluorescence analysis of liver using anti-Alb(Green) and anti-LacZ(Red) antibodies showed that Cre is expressed in most hepatocytes.

alb-creERT2-3.png

Fig3  Blood biochemical assay of Alb-CreERT2 male and female mice. Alb-CreERT2 mice do not display any liver functional abnormalities.

Publications 1piece

1. Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress
Published year：2019-12-03 References：Cell Reports

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