hCIDEB

Nomenclature

C57BL/6Smoc-Cidebtm1(hCIDEB)Smoc

Cat. NO.

NM-HU-233513

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Cideb

Model Description

The endogenous mouse Cideb gene was replaced by human CIDEB gene.

Validation Data

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Fig.1 Detection of CIDEB expression in small intestine and liver by RT-PCR. 

Wild type: only one band at 197 bp with primers F1/R1(mCideb);

Homozygous: only one band at 153 bp with primers F2/R2(hCIDEB).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of CIDEB expression in small intestine and liver by qPCR (male, 6-8wks, n=2).

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Fig.3 Detection of human CIDEB expression in hCIDEB knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous. 

Note. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.

image.png

Fig.4 Blood biochemical detection of hCIDEB knokcin mice. (n=3, male, 8-week-old, Mean±SEM).

Abbr. HO, homozygous; WT, wild type.


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