SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Tnfsf4tm2(hTNFSF4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200263
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Strain Name：C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Cd8atm1(V5-IRES-luc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210375
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Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Ctla4tm1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Tnfsf4tm1(hTNFSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00070
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Tnfsf4tm2(TNFSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200005
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00015
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Pdcd1tm1(hPDCD1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190079
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd8atm1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210373
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Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000096
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000097
Research Application：Immunotherapy,cancer research,drug screening
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