Models

Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210349
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Vtcn1tm1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Vtcn1tm2(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190075
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Btlatm2(hBTLA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190040
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Ccr8tm3(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220074
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Ccr8tm3(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220073
Mice
Strain Name:C57BL/6Smoc-Ccr8tm1(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210435
Mice
Strain Name:C57BL/6Smoc-Ccr8tm1(hCCR8)Pdcd1tm1(hPDCD1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210400
Mice
Strain Name:C57BL/6Smoc-Bsgtm1(hBSG)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000021
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd160tm1(CD160)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190057
Research Application:Immunotherapy,cancer research,drug screening
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