SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：BALB/cJSmo-Cd28tm(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220509
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Strain Name：C57BL/6JSmo-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Cd28tm2(hCD28)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-232307
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Strain Name：C57BL/6JSmo-Cd28tm2(hCD28)Folh1tm1(hPSMA-Wpre-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-233160
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Strain Name：C57BL/6JSmo-Cd300ldtm1(hCD300LD)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-234133
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Strain Name：C57BL/6JSmo-Cd33tm3(CD33)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200002
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd37tm1(hCD37)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225029
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Strain Name：C57BL/6JSmo-Cd38tm2(CD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190059
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Cd3etm2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210023
Research Application：inmmue therapy；drug screening
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