hCD28(BALB/c,3)

Nomenclature

BALB/cAnSmoc-Cd28tm(hCD28)Smoc

Cat. NO.

NM-HU-220509

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
CD28

Synonyms

NCBI ID

12487

MGI ID

88327

Ensembl ID

ENSMUSG00000026012

Pubmed

CD28

Human Ortholog

CD28

Model Description

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Validation Data

image.png

Fig1. Detection of hCD28 expression on T cells in blood in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig2. Detection of hCD28 expression on T cells in spleen in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

image.png

Fig3. Detection of hCD28 expression on T cells in thymus in hCD28(3) KI mice. 

(A) Human CD28 expression on CD4+ and CD8+ T cells in hCD28 mice; (B) Statistics of CD28+ cell populations in hCD28 mice.

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