SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Ms4a1tm2(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220035
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E))Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210233
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E))Cd38tm2(hCD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210234
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220027
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210449
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Sdc1tm1(hSDC1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220021
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220120
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Strain Name：BALB/cJSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Strain State：Repository Live | Cat. NO.：NM-HU-220122
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Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220110
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Strain Name：C57BL/6JSmo-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Cd276tm(hCD276)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220250
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