SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Lair1tm2(LAIR1)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220040
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Strain Name：C57BL/6Smoc-Lgals9tm(hLGALS9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215009
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Strain Name：C57BL/6Smoc-Marcotm1(hMARCO)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000029
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Ncr1tm1(hNCR2 )Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215068
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Strain Name：C57BL/6Smoc-Ncr1tm1(hNCR3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215066
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Strain Name：C57BL/6Smoc-Tgtn( hNCR3LG1)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-220286
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Strain Name：C57BL/6Smoc-Nkg2tm1(hNKG2A)Cd94tm1(hCD94)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000016
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Nrp1tm1(hNRP1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225046
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Strain Name：C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00041
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00078
Research Application：cancer research,Immunotherapy,drug screening
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